Abstract: Data Science is one of the buzzwords of the last few years. According to Harvard Business Review the Data Scientist is the sexiest job of the 21st century. When I started 15 years ago as an OR Engineer, that was for sure the sexiest job at that time. So, are these just buzzwords or is there really a difference? What is the effect of the enormous amount of data generated these days, and how is this effecting the application of OR today? And why are techniques like neural nets and machine learning suddenly so popular? Just because there is more audience does not mean the game is any different. In this talk I will discuss from several viewpoints (business and academic) how Data Science could be seen as a game changer for OR, but also the other way around. So what’s in a name?